| Accession |
PRJCA006440 |
| Title |
scRNA-seq of rat testicular interstitial cells |
| Relevance |
Model organism |
| Data types |
Single cell sequencing
|
| Organisms |
Rattus
|
| Description |
Stem Leydig cells (SLCs) play a critical role in the development and maintenance of adult Leydig cell (ALC) population. To further characterize SLCs in adult testis, we have analyzed 3 rat testicular interstitial cell samples by single-cell RNA-seq technique. The 3 samples came from normal control, 1 week and 3 weeks post ethanedimethanesulfonate (EDS) treated rats whose ALCs were eliminated by 1 week and partially regenerated by 3 weeks. The dataset is useful for identification and characterization of interstitial compartment cells of adult rat testis. |
| Sample scope |
Single cell |
| Release date |
2022-02-21 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 35242757
|
Identification of Rat Testicular Leydig Precursor Cells by Single-Cell-RNA-Sequence Analysis
|
Frontiers in Cell and Developmental Biology
|
10.3389/fcell.2022.805249
|
2022
|
| 39229372
|
Effects of Leydig cell elimination on testicular interstitial cell populations: characterization by scRNA-seq and immunocytochemical techniques
|
Frontiers in Endocrinology
|
10.3389/fendo.2024.1423801
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
Major Research Plan
|
91949123
|
Molecular mechanism of miR-299a-5p/NF-kB regulatory loop promoting testicular Leydig cell aging
|
|
|
| Submitter |
Haolin
Chen (hchen100@yahoo.com)
|
| Organization |
The Second Affiliated Hospital of Wenzhou Medical University |
| Submission date |
2021-09-05 |
