Accession PRJCA006620
Title Genome-wide investigation of effects of aberrant DNA methylation on the usage of alternative promoters in hepatocellular carcinoma
Relevance Medical
Data types Epigenomics
Transcriptome or Gene expression
Raw sequence reads
Organisms Homo sapiens
Description In this study, we systematically elaborated the overview usage of promoters in HCC. Different from previous studies concerned with gene expression, our study focused on pre-transcriptional regulation suggest that promoter activity was more effective and conducive for tumorigenesis exploration. Then the correlation between APs activity and methylation status indicated that APs activity could be regulated by the aberrant methylation status.
Sample scope Monoisolate
Release date 2022-01-04
Grants
Agency program Grant ID Grant title
Fundamental Research Funds for the C Fundamental Research Funds for the Central Universitiesentral Universities 2021GCRC073
Submitter Ximiao    He  (XimiaoHe@hust.edu.cn)
Organization Huazhong University of Science & Technology
Submission date 2021-09-18

Project Data

Resource name Description
BioSample (4) -
SAMC1910174 Para cancer tissue of GX157272
SAMC1910169 HCC tissue of GX157272
SAMC1910166 Para cancer tissue of GX15405
SAMC1910162 HCC tissue of GX15404