| 项目编号 |
PRJCA006829 |
| 项目标题 |
The m6A reader PRRC2A is essential for successful completion of meiosis I in spermatogenesis by promoting mRNA stability |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Transcriptome or Gene expression
Raw sequence reads
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
To explore the mechanism that PRRC2A regulates spermatogenesis, we adopted RNA-seq of P20 Prrc2a-cko and control testes to evaluate PRRC2A deficiency caused disorder of transcriptome. Furthermore, we performed PRRC2A RIP-seq using P20 Prrc2a-flag mouse testes to identify the m6A modification of testes transcripts. Taken together, to figure out the function of PRRC2A in spermatogenesis. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2023-03-02 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 36964127
|
The m6A reader PRRC2A is essential for meiosis I completion during spermatogenesis
|
Nature Communications
|
10.1038/s41467-023-37252-y
|
2023
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Chinese Academy of Sciences (CAS)
|
Youth Innovation Promotion Association
|
2020104
|
|
|
|
| 提交者 |
Caihong
Zheng (zhengch@big.ac.cn)
|
| 提交单位 |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| 提交日期 |
2021-10-11 |
