项目编号 PRJCA006987
项目标题 Gut microbiota-derived metabolic abnormalities of sphingosine contribute to testicular cell apoptosis in a prediabetic model
涉及领域 Medical
数据类型 Single cell sequencing
物种名称 Ovis aries
描述信息 Our results reveal that sphingosine contributed to the disruption of spermatogenesis and could be a disease marker; furthermore, melatonin represents a potential prebiotic agent for the treatment of male infertility caused by prediabetes and its complications.
样品范围 Single cell
发布日期 2021-12-17
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
33807577 Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma International Journal of Molecular Sciences 10.3390/ijms22052602 2021
35606800 Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep BMC Biology 10.1186/s12915-022-01326-y 2022
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) General Program 31900595
National Natural Science Foundation of China (NSFC) General Program 32000582
提交者 Sun Peng (1318329288@qq.com)
提交单位 Inner Mongolia University
提交日期 2021-10-26

项目包含数据信息

资源名称 描述
BioSample (3) -
SAMC477330 scRNA_seq of ovis aries:adult male testis
SAMC477329 scRNA_seq of ovis aries:adult male testis
SAMC477328 scRNA_seq of ovis aries:adult male testis
GSA (1) -
CRA005278 Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep