| 项目编号 |
PRJCA006987 |
| 项目标题 |
Gut microbiota-derived metabolic abnormalities of sphingosine contribute to testicular cell apoptosis in a prediabetic model |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
Ovis aries
|
| 描述信息 |
Our results reveal that sphingosine contributed to the disruption of spermatogenesis and could be a disease marker; furthermore, melatonin represents a potential prebiotic agent for the treatment of male infertility caused by prediabetes and its complications. |
| 样品范围 |
Single cell |
| 发布日期 |
2021-12-17 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 33807577
|
Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma
|
International Journal of Molecular Sciences
|
10.3390/ijms22052602
|
2021
|
| 35606800
|
Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep
|
BMC Biology
|
10.1186/s12915-022-01326-y
|
2022
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31900595
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
32000582
|
|
|
| 提交者 |
Sun
Peng (1318329288@qq.com)
|
| 提交单位 |
Inner Mongolia University |
| 提交日期 |
2021-10-26 |