| Accession |
PRJCA006987 |
| Title |
Gut microbiota-derived metabolic abnormalities of sphingosine contribute to testicular cell apoptosis in a prediabetic model |
| Relevance |
Medical |
| Data types |
Single cell sequencing
|
| Organisms |
Ovis aries
|
| Description |
Our results reveal that sphingosine contributed to the disruption of spermatogenesis and could be a disease marker; furthermore, melatonin represents a potential prebiotic agent for the treatment of male infertility caused by prediabetes and its complications. |
| Sample scope |
Single cell |
| Release date |
2021-12-17 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33807577
|
Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma
|
International Journal of Molecular Sciences
|
10.3390/ijms22052602
|
2021
|
| 35606800
|
Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep
|
BMC Biology
|
10.1186/s12915-022-01326-y
|
2022
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31900595
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
32000582
|
|
|
|
| Submitter |
Sun
Peng (1318329288@qq.com)
|
| Organization |
Inner Mongolia University |
| Submission date |
2021-10-26 |
