Accession PRJCA007122
Title 2018YFC0910200-Standard Reference Data Set of Chinese Human Cell Transcriptome and Translation Group Sequencing
Relevance Medical
Data types Whole genome sequencing
Transcriptome or Gene expression
Genome sequencing and assembly
翻译组RNC-seq
Organisms Komagataella pastoris
Homo sapiens
Description In recent years, with the rapid development of bioomics research, including genomics, transcriptomics, translatomics and proteomics, and the cross application of biological information and big data science, a new medical concept and medical model, precision medicine, has been bred.Life omics research is one of the most important means to reveal disease mechanism and precision medicine. The data quality of omics is directly related to the accuracy of disease mechanism and the effectiveness of precision medicine. However, due to the diversity of sample processing methods, the diversity of determination platforms and the imprecision of analysis technology, the current omics data has poor repeatability and experimentality of cross platform and cross laboratory data.Therefore, by establishing the quality standard of personal genome assembly and testing the consistency of the standard sample MHCC97H, this subject has established a high-precision sequencing process of genome, transcriptome and translatomics ; At the same time, establish the whole process of protein mass spectrometry data acquisition, including standard operating procedures for qualitative and quantitative detection, and establish open search quality control standards, in order to control the data quality of each group in the whole process and in multiple directions.
Sample scope Monoisolate
Release date 2022-12-16
Publication
PubMed ID Article title Journal name DOI Year
30828383
32694877
32212716
33343834
33297998
32318910
31340039
31168775
31178895
30626072
A stable reference human transcriptome and proteome as a standard for reproducible omics experiments bioRxiv 10.1101/2022.11.16.516732 2022
Grants
Agency program Grant ID Grant title
National Health Commission of the People's Republic of China National Key R&D Program of China 2018YFC0910200 Research, development and application demonstration of key technologies for proteomic data quality control
Submitter Hong Lu (1926226931@qq.com)
Organization Jinan University
Submission date 2021-11-05

Project Data

Resource name Description
BioSample (206)  show -
GSA (1) -
CRA005458 2018YFC0910201-Quantitative accuracy assessment data of transcriptome/translation group under different sequencing depths