| 项目编号 |
PRJCA007142 |
| 项目标题 |
single-cell RNA sequencing and Bulk RNA sequencing datasets of both control and acute aristolochic acid treated mice |
| 涉及领域 |
Model organism |
| 数据类型 |
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
In this study, we employed single-cell RNA sequencing and bulk RNA sequencing to compare AA-treated mouse kidney with healthy mouse kidney to comprehensively interrogate the renal tissue microenvironment that is substantially remodeled by AAI treatment. We aimed to comprehensively characterized the dynamic changes in transcriptomic features, and cellular state after AAI treatment, providing novel insight into the molecular mechanism, as well as identifying potential therapeutic targets of AAN. |
| 样品范围 |
Single cell |
| 发布日期 |
2024-05-26 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 35852860
|
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy
|
JCI Insight
|
10.1172/jci.insight.157360
|
2022
|
|
|
| 实验材料提供者 |
Artemisinin Research Center, and Institute of Chinese Materia Medica |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82074098
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81841001
|
|
|
|
| 提交者 |
yunmeng
bai (2856450699@qq.com)
|
| 提交单位 |
Shenzhen People's Hospital |
| 提交日期 |
2021-11-09 |
