| Accession | PRJCA007579 | ||||||||||||||||
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| Title | Integrative analysis of transcriptomics and epigenomics of hypertrophic cardiomyopathy | ||||||||||||||||
| Relevance | hypertrophic cardiomyopathy | ||||||||||||||||
| Data types |
Epigenomics
Transcriptome or Gene expression |
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| Organisms |
Mus musculus
Musculus Homo sapiens |
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| Description | Hypertrophic cardiomyopathy (HCM) is an inherited disorder that can leads to atrial fibrillation, heart failure and arrhythmic sudden death. It is characterized by unexplained left-ventricular hypertrophy. In this study, we collected 12 adult human left ventricles from HCM patients and used 8 adult human left ventricles from healthy donors who contributed for other reasons instead of cardiovascular disease and 3 fetal human left ventricles from aborted fetuses. To explore the mechanism of hypertrophic cardiomyopathy, we performed bulk RNA-seq and NOMe-seq for the left ventricle samples. | ||||||||||||||||
| Sample scope | Monoisolate | ||||||||||||||||
| Release date | 2024-06-26 | ||||||||||||||||
| Publication |
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| Grants |
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| Submitter | Fuchou Tang (tangfuchou@pku.edu.cn) | ||||||||||||||||
| Organization | Peking University | ||||||||||||||||
| Submission date | 2021-12-15 |