Accession PRJCA007744
Title scRNA-seq of liver cancer
Relevance Medical
Data types Single cell sequencing
Organisms Homo sapiens
Description scRNA-seq of liver cancer
Sample scope Single cell
Release date 2022-07-29
Publication
PubMed ID Article title Journal name DOI Year
36352227 Liver tumour immune microenvironment subtypes and neutrophil heterogeneity Nature 10.1038/s41586-022-05400-x 2022
37437101 Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression Journal of Leukocyte Biology 10.1093/jleuko/qiad069 2023
40571730 Multi-omic analysis of gallbladder cancer identifies distinct tumor microenvironments associated with disease progression Nature Genetics 10.1038/s41588-025-02236-9 2025
41005980 Targeting SQLE-mediated cholesterol metabolism to enhance CD8+ T cell activation and immunotherapy efficacy in hepatocellular carcinoma Journal for Immunotherapy of Cancer 10.1136/jitc-2025-012345 2025
39548460 Multi-omics-driven discovery of invasive patterns and treatment strategies in CA19-9 positive intrahepatic cholangiocarcinoma Journal of Translational Medicine 10.1186/s12967-024-05854-9 2024
39966876 Integration of single-cell and spatial transcriptomics reveals fibroblast subtypes in hepatocellular carcinoma: spatial distribution, differentiation trajectories, and therapeutic potential Journal of Translational Medicine 10.1186/s12967-025-06192-0 2025
41219194 Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma Nature Communications 10.1038/s41467-025-64860-7 2025
39239526 DAB2 + macrophages support FAP + fibroblasts in shaping tumor barrier and inducing poor clinical outcomes in liver cancer Theranostics 10.7150/thno.99046 2024
40443016 Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma Cancer Communications 10.1002/cac2.70036 2025
39448202 Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells Journal for Immunotherapy of Cancer 10.1136/jitc-2024-010148 2024
41491934 Multi-omics profiling reveals that Scissor + epithelial cells regulate intrahepatic metastasis of HCC via remodeling the metastatic microenvironment Cellular Oncology 10.1007/s13402-025-01147-5 2026
39636298 Tumor-associated neutrophils attenuate the immunosensitivity of hepatocellular carcinoma The Journal of Experimental Medicine 10.1084/jem.20241442 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82030079
National Natural Science Foundation of China (NSFC) 82173035
Submitter Ruidong Xue (rxue@hsc.pku.edu.cn)
Organization Peking University First Hospital
Submission date 2021-12-29

Project Data

Resource name Description
BioSample (338)  show -