项目编号 PRJCA007982
项目标题 Analysis of chromosome ploidy in infants with embryonic chromosomal mosaicism by single-cell multi-omics sequencing
涉及领域 Medical
数据类型 Whole genome sequencing
Transcriptome or Gene expression
Raw sequence reads
Genome sequencing
Single cell sequencing
物种名称 Homo sapiens
描述信息 While knowing the consequence of embryonic chromosomal mosaicism is important for both IVF pregnancy and natural conception, postnatal evaluation of transferred mosaic embryos is not sufficient, which is mainly focused on the rates of pregnancy and birth, whereas data on high resolution postnatal karyotyping and chromosome testing are still lacking. Here we performed single-cell multi-omics sequencing for peripheral white blood cells obtained from 7 infants with embryonic chromosomal mosaicism to explore their chromosome ploidy status at single-cell resolution.
样品范围 Single cell
发布日期 2022-07-26
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
35944838 Single-cell Sequencing Reveals Clearance of Blastula Chromosomal Mosaicism in In Vitro Fertilization Babies Genomics, Proteomics & Bioinformatics 10.1016/j.gpb.2022.07.004 2022
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
the National Key R&D Program of China 2018YFC100310
提交者 Fuchou Tang (tangfuchou@pku.edu.cn)
提交单位 Peking University
提交日期 2022-01-17

项目包含数据信息

资源名称 描述
BioSample (10)  show -