| 项目编号 | PRJCA008454 | ||||||||||||||||||||
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| 项目标题 | ABO affect gut microbiota | ||||||||||||||||||||
| 涉及领域 | Environmental | ||||||||||||||||||||
| 数据类型 |
Metagenome
Phenotype or Genotype Transcriptome or Gene expression Raw sequence reads |
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| 物种名称 |
Erysipelotrichaceae bacterium OH741_COT-311
metagenome pig metagenome Sus scrofa |
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| 描述信息 | We have analyzed the composition of the intestinal microbiota at different ages and anatomical locations in > 1,800 mosaic 6th- and 7th-generation animals. We show that, under such conditions of exacerbated genetic diversity and environmental uniformity, microbiota composition and abundance of specific taxa are heritable in this species. We map a quantitative trait locus with major effect on the abundance of Erysipelotrichaceae species to chromosome 1q and show that it is caused by a common 2.3-Kb deletion inactivating the N-acetyl-galactosaminyl-transferase gene underpinning the ABO blood group in human. | ||||||||||||||||||||
| 样品范围 | Multispecies | ||||||||||||||||||||
| 发布日期 | 2022-03-08 | ||||||||||||||||||||
| 出版信息 |
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| 项目资金来源 |
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| 提交者 | Congying Chen (chcy75@hotmail.com) | ||||||||||||||||||||
| 提交单位 | State Key Laboratory of Pig Genetic Improvement and Production Technology | ||||||||||||||||||||
| 提交日期 | 2022-02-26 |