Accession PRJCA008567
Title Single cell dissection of epithelial-immune cellular interplay in acute kidney injury microenvironment
Relevance Medical
Data types Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
Organisms Mus musculus
Description We employed unbiased single-cell RNA sequencing to systematically resolve the cellular atlas of kidney tissue samples from mice at 1, 2 and 3 days after ischemia-reperfusion AKI and healthy control. The single-cell transcriptome findings were validated using multiplex immunostaining, western blotting, and functional experiments.
Sample scope Single cell
Release date 2022-03-14
Publication
PubMed ID Article title Journal name DOI Year
35603220 Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment Frontiers in Immunology 10.3389/fimmu.2022.857025 2022
37533253 Single-cell dissection of cellular and molecular features underlying mesenchymal stem cell therapy in ischemic acute kidney injury Molecular Therapy 10.1016/j.ymthe.2023.07.024 2023
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) National Key R&D Program of China 2017YFA0103203
Submitter Min Zhang (mzhangcool@yeah.net)
Organization the Fifth Medical Center of PLA General Hospital
Submission date 2022-03-07

Project Data

Resource name Description
BioSample (4) -
SAMC628420 AKI72h
SAMC628419 AKI48h
SAMC628418 AKI24h
SAMC628417 Control
GSA (1) -
CRA006298 Single cell dissection of epithelial-immune cellular interplay in acute kidney injury microenvironment