| 项目编号 |
PRJCA008573 |
| 项目标题 |
Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Homo sapiens
Homo
|
| 描述信息 |
Cervical squamous cell carcinoma (CESC) is a prototypical human cancer with well-characterized pathological stages of initiation and progression. However, high-resolution knowledge of the transcriptional programs underlying each stage of CESC is lacking, and important questions remain. We performed single-cell RNA sequencing of 76,911 individual cells from 13 samples of human cervical tissues at various stages of malignancy. |
| 样品范围 |
Single cell |
| 发布日期 |
2022-12-20 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 36706185
|
Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression
|
Science Advances
|
10.1126/sciadv.add8977
|
2023
|
| 39354287
|
Dissecting the Single-Cell Diversity and Heterogeneity Underlying Cervical Precancerous Lesions and Cancer Tissues
|
Journal of Animal Ecology
|
10.1007/s43032-024-01695-5
|
2024
|
| 40439976
|
To explore the molecular mechanisms and shared genetic characteristics of rheumatoid arthritis and cervical cancer based on multiple omics and clinical samples
|
Discover Oncology
|
10.1007/s12672-025-02741-7
|
2025
|
| 41042872
|
Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection
|
Science Advances
|
10.1126/sciadv.ady1640
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
National Key Research and Development Projects of China
|
2018YFC1312201
|
|
|
|
| 提交者 |
Jinming
Yu (sdyujinming@126.com)
|
| 提交单位 |
Shandong First Medical University and Shandong Academy of Medical Sciences |
| 提交日期 |
2022-03-07 |
