| Accession |
PRJCA009305 |
| Title |
Single-cell RNA sequencing reveals the effects of artesunate in the treatment of sepsis-induced liver injury |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Single cell sequencing
|
| Organisms |
Mus musculus
|
| Description |
We performed single-cell RNA transcriptome sequencing (scRNA-seq) to profile liver cells in cecal ligation and puncture (CLP)-induced sepsis model, and found that ART could mitigate sepsis-induced injury, inflammation and dysfunction of hepatic cells (like endothelial cells, macrophages, lymphocytes, and neutrophils), supplying the foundation for the application of ART in liver protection, which would highlight its clinical potentials for sepsis therapy. |
| Sample scope |
Single cell |
| Release date |
2024-04-25 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81903588
|
|
|
|
| Submitter |
yunmeng
bai (2856450699@qq.com)
|
| Organization |
Shenzhen People's Hospital |
| Submission date |
2022-04-25 |
