| Accession |
PRJCA010164 |
| Title |
RNA-seq analysis of MTDH knockdown HUVECs |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
In monochorionic twins with selective intrauterine growth restriction, MTDH was significantly downregulated in IUGR twin placentas compared with that of the normal cotwins. Knockdown of MTDH in HUVECs resulted in the inhibition of proliferation, migration, tube formation and spheroid sprouting. To verify whether MTDH is required in placental development and fetal growth, we knocked down MTDH in HUVECs and performed RNA-Seq analysis. |
| Sample scope |
Monoisolate |
| Release date |
2023-05-05 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81971399
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82171661
|
|
|
|
| Submitter |
Yuan
Wei (weiyuanbysy@163.com)
|
| Organization |
Peking University Third Hospital |
| Submission date |
2022-06-19 |
