| 项目编号 | PRJCA010171 | ||||||||||||||||||||||||
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| 项目标题 | Whole-exome sequencing study of familial nasopharyngeal carcinoma and its implication for identifying high-risk individuals | ||||||||||||||||||||||||
| 涉及领域 | Medical | ||||||||||||||||||||||||
| 数据类型 | Variation | ||||||||||||||||||||||||
| 物种名称 | Homo sapiens | ||||||||||||||||||||||||
| 描述信息 | Nasopharyngeal carcinoma is closely associated with genetic factors and Epstein-Barr virus infection, showing significant familial aggregation. Individuals with a family history suffer elevated NPC risk, requiring effective genetic counseling for risk stratification and individualized prevention. We performed whole-exome sequencing on 502 familial NPC patients and 404 unaffected relatives and controls. We systematically evaluated the established cancer predisposition genes and investigated novel NPC susceptibility genes. | ||||||||||||||||||||||||
| 样品范围 | Monoisolate | ||||||||||||||||||||||||
| 发布日期 | 2024-06-21 | ||||||||||||||||||||||||
| 项目资金来源 |
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| 提交者 | Wei-Hua Jia (jiawh@sysucc.org.cn) | ||||||||||||||||||||||||
| 提交单位 | Sun Yat-sen University Cancer Center | ||||||||||||||||||||||||
| 提交日期 | 2022-06-21 |
| 资源名称 | 描述 |
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| BioSample (906) show | - |