Accession

PRJCA010189

Title

The identification and characterization of novel chromatin regulators in the maintenance and conversion of pluripotency states.

Relevance

Model organism

Data types

Whole genome sequencing
Epigenomics
Transcriptome or Gene expression

Organisms

Mus musculus
Homo sapiens

Description

To explore the changes in the gene transcription, histone modifications, chromatin accessibility states and transcription factor genome-wide distribution during the development of embryo and tumor genesis, we performed ChIP-Seq, ATAC-Seq, RNA-Seq, MeRIP-Seq, WGBS in mouse embryo, mESC, and human cell lines.

Sample scope

Multispecies

Release date

2022-06-22

Grants

Agency	program	Grant ID	Grant title
Ministry of Science and Technology of the People's Republic of China (MOST)	National Key Technologies R&D Program	2017YFA0504102

Submitter

Xudong Wu (wuxudong@tmu.edu.cn)

Organization

Tianjin Medical University

Submission date

2022-06-22

Project Data

Resource name	Description
BioSample (120) show	-
SAMC2174028	sgCRTC2_2
SAMC2174024	sgCRTC2_1
SAMC2174020	sgControl_2
SAMC2174017	sgControl_1
SAMC2174013	CRTC2TY1_input
SAMC2174009	CRTC2TY1_ChIP
SAMC2174005	shALKBH5-m6A-Hyp
SAMC2174001	shScr-m6A-Nor
SAMC2173998	WT-m6A-Hyp
SAMC2173992	WT-m6A-Nor
SAMC2173989	shALKBH5-Hyp
SAMC2173985	shScr-Nor
SAMC2173981	WT-Hyp
SAMC2173978	WT-Nor
SAMC2173976	shPRMT2-H3R8me2as
SAMC2173973	shPRMT2-H3K9me3
SAMC2173970	shPRMT2-H3K27ac
SAMC2173967	shPRMT2-H3K27me3
SAMC2173961	shPRMT2-H3K4me3
SAMC2173956	shPRMT2-H3K4me1
SAMC2173953	shScr-H3R8me2as
SAMC2173949	shScr-H3K9me3
SAMC2173945	shScr-H3K27ac
SAMC2173942	shScr-H3K27me3
SAMC2173938	shScr-H3K4me3
SAMC2173933	shScr-H3K4me1
SAMC808481	VPR-T-GFP-T-Lib-control-2
SAMC808480	VPR-T-GFP-T-Libdox-2
SAMC808479	VPR-T-GFP-T-Lib-input-2
SAMC808478	VPR-T-GFP-T-Lib-control-1
SAMC808477	VPR-T-GFP-T-Libdox-1
SAMC808476	VPR-T-GFP-T-Lib-input-1
SAMC808475	WT-SL WGBS
SAMC808474	MT-SL WGBS
SAMC808473	WT-SL RNA-seq rep2
SAMC808472	WT-SL RNA-seq rep1
SAMC808471	WT-2i RNA-seq rep2
SAMC808470	WT-2i RNA-seq rep1
SAMC808469	MT-SL RNA-seq rep2
SAMC808468	MT-SL RNA-seq rep1
SAMC808467	MT-2i RNA-seq rep2
SAMC808466	MT-2i RNA-seq rep1
SAMC808465	WT-SL Ring1b rep1
SAMC808464	WT-SL H3K36me2 rep5
SAMC808463	WT-SL H3K36me2 rep4
SAMC808462	WT-SL H3K36me2 rep3
SAMC808461	WT-SL H3K36me2 rep2
SAMC808460	WT-SL H3K36me2 rep1
SAMC808459	WT-SL H3K27me3 rep3
SAMC808458	WT-SL H3K27me3 rep2
SAMC808457	WT-SL H3K27me3 rep1
SAMC808456	WT-SL H2AK119ub1
SAMC808455	WT-SL Ezh2 rep2
SAMC808454	WT-SL Ezh2 rep1
SAMC808453	WT-SL Brg1 rep2
SAMC808452	WT-SL Brg1 rep1
SAMC808451	WT-2i Ring1b rep1
SAMC808450	WT-2i Kdm2b rep2
SAMC808449	WT-2i Kdm2b rep1
SAMC808448	WT-2i H3K36me2 rep3
SAMC808447	WT-2i H3K36me2 rep2
SAMC808446	WT-2i H3K36me2 rep1
SAMC808445	WT-2i H3K27me3 rep3
SAMC808444	WT-2i H3K27me3 rep2
SAMC808443	WT-2i H3K27me3 rep1
SAMC808442	WT-2i H2AK119ub1
SAMC808441	WT-2i Ezh2 rep3
SAMC808440	WT-2i Ezh2 rep2
SAMC808439	WT-2i Ezh2 rep1
SAMC808438	WT-2i Brg1 rep2
SAMC808437	WT-2i Brg1 rep1
SAMC808436	MT-SL Ring1b rep1
SAMC808435	MT-SL H3K36me2 rep5
SAMC808434	MT-SL H3K36me2 rep4
SAMC808433	MT-SL H3K36me2 rep3
SAMC808432	MT-SL H3K36me2 rep2
SAMC808431	MT-SL H3K36me2 rep1
SAMC808430	MT-SL H3K27me3 rep3
SAMC808429	MT-SL H3K27me3 rep2
SAMC808428	MT-SL H3K27me3 rep1
SAMC808427	MT-SL H2AK119ub1
SAMC808426	MT-SL Ezh2 rep3
SAMC808425	MT-SL Ezh2 rep2
SAMC808424	MT-SL Ezh2 rep1
SAMC808423	MT-SL Brg1 rep2
SAMC808422	MT-SL Brg1 rep1
SAMC808421	MT-2i Ring1b rep1
SAMC808420	MT-2i Kdm2b rep2
SAMC808419	MT-2i Kdm2b rep1
SAMC808418	MT-2i H3K36me2 rep3
SAMC808417	MT-2i H3K36me2 rep2
SAMC808416	MT-2i H3K36me2 rep1
SAMC808415	MT-2i H3K27me3 rep3
SAMC808414	MT-2i H3K27me3 rep2
SAMC808413	MT-2i H3K27me3 rep1
SAMC808412	MT-2i H2AK119ub1
SAMC808411	MT-2i Ezh2 rep3
SAMC808410	MT-2i Ezh2 rep2
SAMC808409	MT-2i Brg1 rep2
SAMC808408	MT-2i Brg1 rep1
SAMC808407	WT-SL ATAC-seq rep2
SAMC808406	WT-SL ATAC-seq rep1
SAMC808405	WT-2i ATAC-seq rep2
SAMC808404	WT-2i ATAC-seq rep1
SAMC808403	MT-SL ATAC-seq rep2
SAMC808402	MT-SL ATAC-seq rep1
SAMC808401	MT-2i ATAC-seq rep2
SAMC808400	MT-2i ATAC-seq rep1
SAMC808399	WT E6.5 Epi H3K27me3 Cut&tag
SAMC808398	MT E6.5 Epi H3K27me3 Cut&tag
SAMC808397	WT E6.5 Epi ATAC-seq rep2
SAMC808396	WT E6.5 Epi ATAC-seq rep1
SAMC808395	MT E6.5 Epi ATAC-seq
SAMC808394	WT E6.5 Epi H3K36me2 rep4 Star ChIP-seq
SAMC808393	WT E6.5 Epi H3K36me2 rep3 Star ChIP-seq
SAMC808392	WT E6.5 Epi H3K36me2 rep2 Star ChIP-seq
SAMC808391	WT E6.5 Epi H3K36me2 rep1 Star ChIP-seq
SAMC808390	WT E3.5 ICM H3K36me2 rep2 Star ChIP-seq
SAMC808389	WT E3.5 ICM H3K36me2 rep1 Star ChIP-seq
SAMC808388	MT E6.5 Epi H3K36me2 Star ChIP-seq
GSA (1)	-
CRA007284	The identification and characterization of novel chromatin regulators in the maintenance and conversion of pluripotency states.