| Accession |
PRJCA010335 |
| Title |
Single-cell sequencing reveals the effects of hyperbaric oxygen therapy on the cellular components of tumor microenvironment in of a mouse colon cancer homologous xenografts model in mice |
| Relevance |
Medical |
| Data types |
Single cell sequencing
|
| Organisms |
Mus musculus
|
| Description |
Solid tumors cancers have complex cellular components in the tumor microenvironments. , in which Hypoxia hypoxia playsis an important feature of the solid tumor microenvironment, an important role. Hyperbaric oxygen (HBO) therapy is currently applied as an adjuvant therapy foradjunct to clinical the treatment of various diseases, including some types of tumorscancer. Here, we established aused a mouse model of MC38 colon cancer cell homologous transplantation to explore the underlying cellular mechanisms and treated withinduced by hyperbaric oxygenHBO therapy. We performed single-cell sequencing to comprehensively assess the We described a transcriptome landscape of MC38 colon cancer under hyperbaric oxygenHBO conditions therapy by advanced ScRNA-seq technology. |
| Sample scope |
Single cell |
| Release date |
2022-07-01 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
|
21201910240001588
|
|
|
|
| Submitter |
siyu
xia (syxbestmayer@whu.edu.cn)
|
| Organization |
Jinan University |
| Submission date |
2022-07-01 |
