Accession PRJCA010775
Title CheckMate 914: CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 914
Relevance Medical
Data types biomaker PD-L1/MDSC
Organisms Homo sapiens
Description The study aims to explore the role of the nivolumab and ipilimumab combination compared to placebo and the role of nivolumab monotherapy compared to placebo post-surgery inadded efficacy and safety in preventing disease recurrence and the impact on survival. If the safety profile is acceptable and nivolumab monotherapy or nivolumab combined with ipilimumab is shown to improve DFS, this study would support the approval of nivolumab or nivolumab combined with ipilimumab in treatment-naive advanced RCC patients post-surgery
Sample scope Multiisolate
Release date 2022-07-25
Grants
Agency program Grant ID Grant title
Bristol-Myers Squibb (China) Investment Co., Ltd., Bristol-Myers Squibb Company 2017L04825/2017L04826
Submitter JIAN HUANG (hjgcp2017@163.com)
Organization Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Submission date 2022-07-25

Project Data

Resource name Description