| Accession |
PRJCA011176 |
| Title |
Long Noncoding RNAs in Intrauterine Infec-tion/inflammation-induced Lung Injury |
| Relevance |
Medical |
| Data types |
Genome sequencing and assembly
|
| Organisms |
Rattus norvegicus
|
| Description |
Intrauterine infection/inflammation can result in fetal and neonatal lung injury. However, the biological mechanisms of intrauterine infection/inflammation on fetal and neonatal lung development are poorly known. The study on characteristics of lncRNAs expression in developmental phases of lungs with injury after intrauterine infection/inflammation has not been reported yet. We utilized pregnant Sprague-Dawley (SD) rats inoculated with Escherichia coli (E. coli) suspension as a model and applied next-generation sequencing (NGS) and bioinformatics techniques to perform genome-wide analyses of differentially expressed lncRNAs and mRNAs between the intrauterine infection and control groups. |
| Sample scope |
Multiisolate |
| Release date |
2022-08-13 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 37280583
|
Long noncoding RNA signatures in intrauterine infection/inflammation-induced lung injury: an integrative bioinformatics study
|
BMC Pulmonary Medicine
|
10.1186/s12890-023-02505-5
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Zhejiang Provincial Natural Science Foundation of China
|
|
LY18H040002
|
|
|
|
| Submitter |
Jiarong
Pan (meilisuzhou@zju.edu.cn)
|
| Organization |
Children's Hospital, Zhejiang University School of Medicine |
| Submission date |
2022-08-13 |
