| 项目编号 |
PRJCA011248 |
| 项目标题 |
A single-cell landscape of recipient-derived infiltrates in mouse heart grafts |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
In this study, we used transgenic mice with ubiquitous eGFP expression as recipients to characterize host-derived infiltrates in donor heart grafts and gain insights into the early immune events during acute rejection by scRNAseq. The profiling of differentially expressed genes in migrated cells was further determined by comparing syngrafts and allografts. Further investigation of the recipient-derived infiltrates in the heart graft is also helpful for uncovering the information on cellular signaling networks or cell-cell communications associated with acute allograft rejection. |
| 样品范围 |
Single cell |
| 发布日期 |
2023-10-08 |
| 出版信息 |
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
8217020772
|
|
|
| 提交者 |
Ping
Zhu (nydljl@hotmail.com)
|
| 提交单位 |
Guangdong Provincial People's Hospital |
| 提交日期 |
2022-08-16 |