| Accession |
PRJCA011266 |
| Title |
Soluble CD14 and CD55 cooperatively promote human cytomegalovirus infection in immature biliary epithelial cells |
| Relevance |
Medicine |
| Data types |
Raw sequence reads
Proteomic data by mass spectrometry
|
| Organisms |
Homo sapiens
|
| Description |
Upregulation of soluble CD14 and CD55 cooperatively promote human cytomegalovirus infection in immature biliary epithelial cells and lead to PARP-1 mediated cell death. CD14 antibody and PARP-1 inhibitor PJ34 treatment in mouse CMV infected model results in reducing mortality and ameliorating of bile duct damage |
| Sample scope |
Monoisolate |
| Release date |
2023-08-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
CD14 facilitates perinatal human cytomegalovirus infection in biliary epithelial cells via CD55
|
JHEP Reports
|
10.1016/j.jhepr.2024.101018
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Open Research Fund Program of the State Key Laboratory of Virology of China
|
|
2015IOV006
|
|
| Open Research Fund Program of the State Key Laboratory of Virology of China
|
|
2018IOV005
|
|
| Science and Technology Planning Project of Guangdong Province
|
|
2019B020227001
|
|
| Science and Technology Planning Project of Guangzhou
|
|
202206080002
|
|
| Science and Technology Project of Guangzhou
|
|
2022A04J00862
|
|
| China Postdoctoral Science Foundation
|
|
2022M720894
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82201894
|
|
|
|
| Submitter |
RUIZHONG
ZHANG (cowboy2006@163.com)
|
| Organization |
Guangzhou Women and Children's Medical Center |
| Submission date |
2022-08-18 |
