| Accession |
PRJCA011305 |
| Title |
Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
The authors show that arsenic trioxide, an FDA approved drug, robustly rescues mutant p53, uncover the underlying molecular mechanism, and report the rescue pattern among frequent p53 mutants. |
| Sample scope |
Monoisolate |
| Release date |
2022-08-19 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33357454
|
|
|
|
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2017YFA0506200
|
|
|
|
| Submitter |
Min
Lu (min.lu@shsmu.edu.cn)
|
| Organization |
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine |
| Submission date |
2022-08-19 |
