| Accession |
PRJCA011337 |
| Title |
Identification and functional analysis of variants of MYH6 gene promoter in isolated ventricular septal defects |
| Relevance |
Medical |
| Data types |
sanger sequencing
|
| Organisms |
Homo
|
| Description |
In 604 of the subjects (311 isolated and sporadic ventricular septal defect patients and 293 healthy controls), DNA was extracted from blood samples and MYH6 gene promoter region variants were analyzed by sequencing. Further functional verification was performed by cellular experiments using dual luciferase reporter gene analysis, electrophoretic mobility shift assays, and bioinformatics analysis. |
| Sample scope |
Multiisolate |
| Release date |
2022-08-20 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82170353
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81870288
|
|
| TEDA International Cardiovascular Hospital
|
|
2021-TD-006
|
|
|
|
| Submitter |
JiyYang
Zuo (jiyangzuo@163.com)
|
| Organization |
Tianjin Medical University |
| Submission date |
2022-08-20 |
