Accession PRJCA011589
Title Widespread eccDNA formation in the human sperm
Relevance Medical
Data types Raw sequence reads
Organisms Homo sapiens
Description The landscape of extrachromosomal circular DNA (eccDNA) during mouse spermatogenesis, as well as the biogenesis mechanism and functional implications remain to be explored. Here, we reveal widespread eccDNA formation in mouse spermatocytes, round spermatids, elongated spermatids and sperm cells.
Sample scope Multiisolate
Release date 2025-01-08
Publication
PubMed ID Article title Journal name DOI Year
Microhomology-Mediated Circular DNA Formation from Oligonucleosomal Fragments During Spermatogenesis BioRxiv 10.1101/2023.02.27.530352 2023
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2021YFF1201500
National Natural Science Foundation of China (NSFC) General Program 32170653
Submitter Jiayu Chen (jiayuchen@nju.edu.cn)
Organization Nanjing University
Submission date 2022-08-31

Project Data

Resource name Description
BioSample (3) -
SAMC2306344 HmSperm_3
SAMC2306339 HmSperm_2
SAMC2306336 HmSperm_1