| Accession |
PRJCA011589 |
| Title |
Widespread eccDNA formation in the human sperm |
| Relevance |
Medical |
| Data types |
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
The landscape of extrachromosomal circular DNA (eccDNA) during mouse spermatogenesis, as well as the biogenesis mechanism and functional implications remain to be explored. Here, we reveal widespread eccDNA formation in mouse spermatocytes, round spermatids, elongated spermatids and sperm cells. |
| Sample scope |
Multiisolate |
| Release date |
2025-01-08 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Microhomology-Mediated Circular DNA Formation from Oligonucleosomal Fragments During Spermatogenesis
|
BioRxiv
|
10.1101/2023.02.27.530352
|
2023
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2021YFF1201500
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
32170653
|
|
|
| Submitter |
Jiayu
Chen (jiayuchen@nju.edu.cn)
|
| Organization |
Nanjing University |
| Submission date |
2022-08-31 |