| 项目编号 |
PRJCA011604 |
| 项目标题 |
Study on the immune regulation of GSD-related enteropathy and gut microbes in children |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Homo sapiens
human gut metagenome
|
| 描述信息 |
This study intends to study the clinical manifestations, intestinal microecological composition and abundance, endoscopic manifestations and histological characteristics of colonic mucosa, intestinal epithelial barrier and mucosal immunological characteristics of different subtypes of glycogen storage disease (GSD), etc. To screen out the differential microbiota associated with IBD-like enteropathy, target the intestinal microbiota, explore the role and mechanism of the occurrence and development of IBD-like enteropathy, and seek safe and effective treatment methods for such children. |
| 样品范围 |
16s rRNA gene v4 sequencing, Single cell |
| 发布日期 |
2023-10-19 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 38889269
|
Gut Dysbiosis Drives Inflammatory Bowel Disease Through the CCL4L2‐VSIR Axis in Glycogen Storage Disease
|
Advanced Science
|
10.1002/advs.202309471
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences
|
Internal hospital fund
|
KY012021199
|
Study on the immune regulation of GSD-related enteropathy and gut microbes in children
|
|
|
| 提交者 |
Min
Yang (yangmin1008@gdph.org.cn)
|
| 提交单位 |
Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences |
| 提交日期 |
2022-09-01 |
