| Accession |
PRJCA011647 |
| Title |
Role of CD8+ T cell exhaustion in the progression and prognosis of acute respiratory distress syndrome induced by sepsis: a prospective observational study |
| Relevance |
Medical |
| Data types |
clinical information and molecular markers
|
| Organisms |
Homo
|
| Description |
CD8+ T cells are important for protective immunity against antigen and/or inflammatory signals in acute respiratory distress syndrome (ARDS). However, high and sustained antigen and inflammatory stimulation during infection can lead to CD8+ T cell exhaustion. The clinical consequences of CD8+ T cell exhaustion in the development and prognosis of sepsis-induced ARDS are still unknown. The primary objective of this prospective observational study was to determine the relationship between CD8+ T cell exhaustion and the prognosis of ARDS induced by sepsis. |
| Sample scope |
Multiisolate |
| Release date |
2022-09-03 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Young Fund of Zhongshan Hospital
|
|
2018ZSQN47
|
|
|
|
| Submitter |
Lei
Yan (yan.lei1@zs-hospital.sh.cn)
|
| Organization |
Zhongshan Hospital, Fudan University |
| Submission date |
2022-09-03 |
