| Accession |
PRJCA011745 |
| Title |
RNA-seq analysis of skeletal muscle transcriptomes from wild-type and Fnip1f/fHSA-Cre (FNIP1 MKO) mice |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Mus musculus
|
| Description |
We performed RNA-seq analysis on mRNA isolated from gastrocnemius (GC) muscles of the FNIP1 MKO and WT littermate controls. Gene expression validation studies demonstrated that the expression of many genes involved in angiogenesis was induced in the GC muscle of FNIP1 MKO mice compared to WT controls. These data suggest that loss of muscle FNIP1 potently induces angiogenesis in skeletal muscle in vivo. |
| Sample scope |
Multiisolate |
| Release date |
2023-10-11 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 37932296
|
FNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment
|
Nature Communications
|
10.1038/s41467-023-42690-9
|
2023
|
| 38324677
|
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise
|
Science Advances
|
10.1126/sciadv.adj2752
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
91857105
|
|
| National Natural Science Foundation of China (NSFC)
|
|
31922033
|
|
| National Natural Science Foundation of China (NSFC)
|
|
32071136
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
|
2018YFA0800700
|
|
| National Natural Science Foundation of China (NSFC)
|
|
32100922
|
|
|
|
| Submitter |
Zhenji
Gan (ganzj@nju.edu.cn)
|
| Organization |
Nanjing University |
| Submission date |
2022-09-07 |
