| Accession |
PRJCA011997 |
| Title |
Protein machinery with dynamic regulation of chromatin plasticity and its mechanism |
| Relevance |
Evolution |
| Data types |
Protein 3D Structure Data
|
| Organisms |
DNA-binding vector pODB80
|
| Description |
The purpose of this project is to clarify the molecular mechanism of specific DNA interaction mediated by chromatin architecture proteins such as CTCF, reveal the recognition mechanism of insulator DNA sequence and the molecular mechanism of chromatin cyclization mediated by CTCF and other chromatin architecture proteins, and explore the regulatory mechanism of dynamic changes in three-dimensional topological structure of chromatin and its relationship with gene transcription regulation. |
| Sample scope |
Synthetic |
| Release date |
2022-09-20 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
|
2017YFA0504200
|
|
|
|
| Submitter |
Yunran
Zhan (yunranzhan@ibp.ac.cn)
|
| Organization |
Institute of Biophysics Chinese Academy of Sciences |
| Submission date |
2022-09-20 |
