| Accession |
PRJCA012124 |
| Title |
Pathophysiological role of variants of the promoter region of CITED2 gene in sporadic tetralogy patients with cellular func-tion verification |
| Relevance |
Medical |
| Data types |
Sanger sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Tetralogy of Fallot (TOF) is a common congenital heart malformation. Genetic variants in the CITED2 coding region are known to be significantly associated with cardiac malformations, but the role of variants in the CITED2 promoter region in the development of TOF remains unclear. In this study, we investigated CITED2 promoter variants in the DNA of 605 subjects, including 312 TOF patients and 293 unrelated healthy controls, by Sanger sequencing. |
| Sample scope |
Multiisolate |
| Release date |
2022-09-25 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81870288/82170353
|
|
|
|
| Submitter |
Zhuo
Chen (czchloe@163.com)
|
| Organization |
TEDA International Cardiovascular Hospital |
| Submission date |
2022-09-25 |
