| Accession |
PRJCA012140 |
| Title |
Genetic analysis of variants of the MYH6 gene promoter in tetralogy of fallot |
| Relevance |
Medical |
| Data types |
Genome sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Tetralogy of fallot (TOF) is one of the common congenital heart diseases. The MYH6 gene has a critical role in cardiac development but the role of MYH6 promoter variants in patients with ASD has not been explored. In 315 TOF patients, we investigated the MYH6 gene promoter variants and verified the effect on gene expression by using cellular functional experiments and bioinformatics analysis. |
| Sample scope |
Multiisolate |
| Release date |
2022-09-26 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38135727
|
Tetralogy of Fallot: variants of MYH6 gene promoter and cellular functional analyses
|
Pediatric Research
|
10.1038/s41390-023-02955-x
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82170353
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81870288
|
|
| TEDA International Cardiovascular Hospital
|
|
2021-TD-006
|
|
|
|
| Submitter |
JiyYang
Zuo (jiyangzuo@163.com)
|
| Organization |
Tianjin Medical University |
| Submission date |
2022-09-26 |
