| Accession |
PRJCA012340 |
| Title |
Pathophysiological role of genetic variants of ISL1 gene promoter in sporadic Tetralogy of Fallot |
| Relevance |
Medical |
| Data types |
Sanger sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Tetralogy of Fallot is the most common type of cyanotic congenital heart disease in newborns. ISL1 is a master transcription factor in second heart field development, whereas the role of ISL1 gene promoter variants in TOF patients has not been genetically investigated. In this study, we investigated ISL1 promoter variants in 601 subjects, including 308 TOF patients and 293 unrelated healthy controls by Sanger sequencing. |
| Sample scope |
Multiisolate |
| Release date |
2022-10-08 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81870288/82170353
|
|
|
|
| Submitter |
xiuyun
yin (xiuyunyin921@163.com)
|
| Organization |
TEDA International Cardiovascular Hospital |
| Submission date |
2022-10-08 |
