| Accession |
PRJCA012864 |
| Title |
Single-cell and bulk transcriptome study of complex tumor microenvironment in hypopharyngeal carcinoma |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Single cell sequencing
|
| Organisms |
Homo sapiens
|
| Description |
We performed single-cell RNA-seq on hypopharyngeal biopsies from different time and treatment-response groups to explore complex tumor microenvironment. After systematic bioinfomatic analyses, we identified functional gene modules from heterogeneous malignant tumor cells and various non-malignant subtypes with specific functions, both of which could be used for medical applications validated by our own cohort with bulk RNA-seq data and corresponding clinical information. |
| Sample scope |
Single cell |
| Release date |
2022-12-24 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
61721003
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82072997
|
|
| National Key Research and Development Program of China
|
|
2019YFA0906103
|
|
|
|
| Submitter |
Zhen
Xie (zhenxie@tsinghua.edu.cn)
|
| Organization |
Tsinghua University |
| Submission date |
2022-10-30 |
