Accession PRJCA013034
Title The transcriptional heterogeneity of pulmonary neutrophils in ALI/ARDS mice.
Relevance Medical
Data types Single cell sequencing
Organisms Mus musculus
Description Neutrophils play a principal role in the pathogenesis, progression and resolution of acute lung injury (ALI) caused by ARDS; however, the transcriptional and phenotypic heterogeneity of pulmonary neutrophils in ALI/ARDS remains largely unknown. Here, we identified transcriptionally and functionally heterogenous neutrophil subsets within LPS-induced ALI mouse lungs using single-cell RNA sequencing.
Sample scope Single cell
Release date 2022-11-23
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82100089
Submitter Kun    Wang  (Dr_Wangk@tongji.edu.cn)
Organization Shanghai East Hospital
Submission date 2022-11-07

Project Data

Resource name Description
BioSample (19)  show -
GSA (2) -
CRA008837 The transcriptional heterogeneity of pulmonary neutrophils within wild type and IL-10 knockout ALI mice lungs.
CRA008856 The transcriptional heterogeneity of pulmonary neutrophils within ALI mice lungs regulated by IL-10.