| 项目编号 |
PRJCA013034 |
| 项目标题 |
The transcriptional heterogeneity of pulmonary neutrophils in ALI/ARDS mice. |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Neutrophils play a principal role in the pathogenesis, progression and resolution of acute lung injury (ALI) caused by ARDS; however, the transcriptional and phenotypic heterogeneity of pulmonary neutrophils in ALI/ARDS remains largely unknown. Here, we identified transcriptionally and functionally heterogenous neutrophil subsets within LPS-induced ALI mouse lungs using single-cell RNA sequencing. |
| 样品范围 |
Single cell |
| 发布日期 |
2022-11-23 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 36513690
|
Locally organised and activated Fth1 hi neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner
|
Nature Communications
|
10.1038/s41467-022-35492-y
|
2022
|
| 39090662
|
CPT1A‐IL‐10‐mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury
|
Clinical and Translational Medicine
|
10.1002/ctm2.1785
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82100089
|
|
|
|
| 提交者 |
Kun
Wang (Dr_Wangk@tongji.edu.cn)
|
| 提交单位 |
Shanghai East Hospital |
| 提交日期 |
2022-11-07 |
