| 项目编号 | PRJCA013249 | ||||||||||||||||
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| 项目标题 | Whole-Genome Promoter Profiling of Plasma Cell-Free DNA Exhibits Predictive Value for Preterm Birth | ||||||||||||||||
| 涉及领域 | Medical | ||||||||||||||||
| 数据类型 |
Whole genome sequencing
Raw sequence reads |
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| 物种名称 | Homo sapiens | ||||||||||||||||
| 描述信息 | we established a large-scale, multi-center, and case-control study that included 2,590 pregnancies (2,072 full-term and 518 preterm pregnancies) from three independent hospitals to develop a preterm birth classifier. We implemented whole-genome sequencing on their plasma cfDNA and then their promoter profiling (read depth spanning from -1 KB to +1 KB around the transcriptional start site) was analyzed. Using three machine learning models and two feature selection algorithms, classifiers for predicting preterm delivery were developed. | ||||||||||||||||
| 样品范围 | Multiisolate | ||||||||||||||||
| 发布日期 | 2022-11-15 | ||||||||||||||||
| 项目资金来源 |
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| 提交者 | Jia Tang (tony2081129@163.com) | ||||||||||||||||
| 提交单位 | NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute | ||||||||||||||||
| 提交日期 | 2022-11-15 |
| 资源名称 | 描述 |
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| BioSample (2590) show | - |