| Accession |
PRJCA013433 |
| Title |
Purine signaling pathway dysfunction in autism spectrum disorders: evidence from multiple omics data |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Metabolomics
|
| Organisms |
Homo sapiens
|
| Description |
Previous studies have suggested that the dysregulation of purine metabolism may be associated with autism spectrum disorder (ASD). Here, we adopted metabolomics and transcriptomics to verify and explore the underlying molecular mechanism of purine metabolism dysfunction in ASD and identify potential biomarkers within the purine metabolism pathway. |
| Sample scope |
Multiisolate |
| Release date |
2022-11-23 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China
|
the general program
|
81974217
|
A metabolomics-based study of oxidative stress markers associated with the efficacy of sulforaphane for autism spectrum disorders
|
| National Natural Science Foundation of China
|
Youth Science Foundation Program
|
81901388
|
Study of the relationship between abnormal interleukin-8 expression and symptoms of autism spectrum disorders and neurodevelopmental defects
|
| Natural Science Foundation of Hunan Province
|
Youth Science Foundation Program
|
2020JJ5830
|
Interactive effects of air pollution exposure and the RELN gene on the onset and symptom severity of autism spectrum disorders
|
|
|
| Submitter |
Jianjun
Ou (oujianjun@csu.edu.cn)
|
| Organization |
Mental Health Institute of the Second Xiangya Hospital, Central South University |
| Submission date |
2022-11-23 |
