Accession PRJCA013605
Title Single-cell sequencing of clinical samples of pancreatic cancer with liver metastases
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description 18 paired samples from 6 patients were collected from primary pancreatic cancer, portal blood, and liver metastases from each patient. Single-cell sequencing was performed after library building using the 10X V3 kit.
Sample scope Monoisolate
Release date 2022-12-21
Publication
PubMed ID Article title Journal name DOI Year
36706761 Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance Cancer Cell 10.1016/j.ccell.2023.01.001 2023
37659082 Protocol for identifying immune checkpoint on circulating tumor cells of human pancreatic ductal adenocarcinoma by single-cell RNA sequencing STAR Protocols 10.1016/j.xpro.2023.102539 2023
38336855 Immune checkpoints HLA-E: CD94-NKG2A and HLA-C: KIR2DL1 complementarily shield circulating tumor cells from NK-mediated immune surveillance Cell Discovery 10.1038/s41421-024-00646-3 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82172634
National Natural Science Foundation of China (NSFC) 22105137
National Natural Science Foundation of China (NSFC) 81902685
Key Program of the Science and Technology Bureau of Sichuan, China 2021YFSY0007
China Postdoctoral Science Foundation 2020M683324
China Postdoctoral Science Foundation 2022T150449
1.3.5 projects for disciplines of excellence, West China Hospital, Sichuan University ZYYC20013
Submitter Jinen Song (15324456297@163.com)
Organization Sichuan University
Submission date 2022-12-01

Project Data

Resource name Description
BioSample (10)  show -