| Accession |
PRJCA013946 |
| Title |
Jatrorrhizine inhibits colorectal cancer growth by ferroptosis-related genes |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Genome sequencing and assembly
|
| Organisms |
Homo sapiens
|
| Description |
In this project, we investigated the inhibitory effect of Jatrorrhizine on SW480 by intervening SW480 with Jatrorrhizine. Then, the molecular mechanism of colorectal cancer inhibition was further investigated by high-throughput sequencing. The sequenced genes were screened for differentially expressed genes associated with ferroptosis and bioinformatics analysis was performed. Finally, the ferroptosis gene was validated by QPCR assay. |
| Sample scope |
Synthetic |
| Release date |
2023-03-19 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 37710311
|
High-throughput sequencing reveals Jatrorrhizine inhibits colorectal cancer growth by ferroptosis-related genes
|
BMC Medical Genomics
|
10.1186/s12920-023-01619-3
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders
|
|
19-xkjs-05
|
Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders
|
|
|
| Submitter |
Minglin
Ou (minglinou@glmc.edu.cn)
|
| Organization |
GuiLin Medical University |
| Submission date |
2022-12-19 |
