| 项目编号 |
PRJCA014208 |
| 项目标题 |
The role of chromatin plasticity in tissue regeneration and disease |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Transcriptome or Gene expression
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
This topic will focus on chromatin plasticity in tissue regeneration and disease, in the normal physiology, tissue damage repair and lesions, chromatin remodeling complex SWI / SNF important members of chromatin accessibility, spatial conformation and key histone modification, histone modification molecules SETD2 and NSD 2 and related molecules on tissue lesions and repair, clarify the interaction of chromatin regulatory protein and cell signaling pathway TGF- β and the molecular mechanism in embryonic development and tumor development. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-12-05 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 38095539
|
Fimepinostat Impairs NF-κB and PI3K/AKT Signaling and Enhances Gemcitabine Efficacy in H3.3K27M-Diffuse Intrinsic Pontine Glioma
|
Cancer Research
|
10.1158/0008-5472.CAN-23-0394
|
2023
|
| 40246858
|
An oncohistone-driven H3. 3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma
|
Nature Communications
|
10.1038/s41467-025-58795-2
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2022YFA1302704
|
|
|
|
| 提交者 |
Qiaoran
Xi (xiqiaoran@mail.tsinghua.edu.cn)
|
| 提交单位 |
Tsinghua University |
| 提交日期 |
2023-01-04 |
