Accession PRJCA014224
Title Screening and analysis of markers for early diagnosis of acute ischemic kidney injury
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description Renal ischemia-reperfusion injury is one of the main causes of clinical acute kidney injury, with a high mortality rate, and most of the surviving patients have varying degrees of chronic renal insufficiency, especially for children after cardiac surgery. For children with acute kidney injury, there is a delay in creatinine changes early in the course of the disease. Therefore, it is necessary to search for another blood marker for early diagnosis. Previous studies have revealed the sensitivity of mirnas in exosomes to tumor diagnosis, and no studies have been conducted on the role of mirnas in acute kidney injury. Therefore, this study intends to explore the diagnostic value of mirnas in acute kidney injury and seek miRNA markers that can indicate kidney injury.
Sample scope Multiisolate
Release date 2023-01-04
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) Young Scientists Fund 81900618 Mechanism study of hypoxia promoting extracellular vesicles generation of mesenchymal stem cells and enhancing the repair ability of renal ischemia reperfusion injury
Submitter jie sun (liupt666@163.com)
Organization Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine
Submission date 2023-01-04

Project Data

Resource name Description