Accession

PRJCA014464

Title

Proteomic study of tongue coating in gastric cancer patients

Relevance

Medical

Data types

Proteomics

Organisms

Bacteria
Homo sapiens

Description

In this project, 417 tongue coating samples were collected from 365 gastric cancer patients and healthy volunteers, and the proteomic characteristics of tongue coating were quantified and analyzed by PCT-DIA technique. Finally, a gastric cancer screening model based on tongue coating proteome was constructed by machine learning.

Sample scope

Multispecies

Release date

2023-02-03

Publication

PubMed ID	Article title	Journal name	DOI	Year
37771779	5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	Theranostics	10.7150/thno.83163	2023
38191439	In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study	Microbiome	10.1186/s40168-023-01730-8	2024

Biomaterial provider

Tiannan Guo

Grants

Agency	program	Grant ID	Grant title
Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer		JBZX-202006
National Key Research and Development Program of China		2021YFA0910100
Medical Science and Technology Project of Zhejiang Province		WKJ-ZJ-2202
Medical Science and Technology Project of Zhejiang Province		WKJ-ZJ-2104
National Natural Science Foundation of China		82074245
National Natural Science Foundation of China		81973634
National Natural Science Foundation of China		81903842
Natural Science Foundation of Zhejiang Province		LR21H280001
Science and Technology Projects of Zhejiang Province		2019C03049
Program of Zhejiang Provincial TCM Sci-tech Plan		2018ZY006
Program of Zhejiang Provincial TCM Sci-tech Plan		2020ZZ005

Submitter

Xiangdong Cheng (chengxd@zjcc.org.cn)

Organization

Zhejiang Cancer Hospital

Submission date

2022-12-04

Project Data

Resource name	Description
BioSample (4)	-
SAMC2541330	Stage_III-IV_GC
SAMC2541326	Stage_I-II_GC
SAMC2541323	Gastritis
SAMC2541320	Normal