| 项目编号 |
PRJCA014909 |
| 项目标题 |
RNA profiling to elucidate the anti-tumor mechanism of anti-CFH antibody, GT103 in mouse model of lung cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Complement factor H (CFH) regulates complement activation and protect host cells, including tumor cells, from attack by the alternative pathway of complement mediated cytotoxicity. In this study, we aim to explore the anti-tumor and immune stimulatory activity of an anti-CFH antibody, mGT103 in mouse model of lung cancer using bulk and single cell RNA sequencing analysis. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-02-13 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| DOD
|
|
LC180060P1
|
A novel immune-modulating antibody for the treatment of lung cancer.
|
|
|
| 提交者 |
Ruchi
Saxena (ruchi.saxena@duke.edu)
|
| 提交单位 |
Duke University |
| 提交日期 |
2023-02-13 |
