| Accession | PRJCA014927 | ||||||||||
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| Title | Single-cell transcriptomic profiling of human head and neck squamous cell carcinoma | ||||||||||
| Relevance | Medical | ||||||||||
| Data types |
Transcriptome or Gene expression
Raw sequence reads |
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| Organisms | Homo sapiens | ||||||||||
| Description | To comprehensively resolve the tumor ecosystem heterogeneity during different periods of HNSC including initiation, progression, lymph node metastasis, and recurrence, we used scRNA-seq (10X Genomics) to profile malignant and non-malignant cells of 26 fresh samples from 13 patients, including 3 normal tissues (NT), 3 pre-cancer lesions (Pre), 3 early-stage tumors (E), 6 advanced-stage tumors (A), 3 intracapsular metastatic lymph nodes (LN-in), 2 extracapsular metastatic lymph nodes (LN-out), 2 normal lymph nodes (LN-normal), and 4 recurrent tumors (R), among which NT-pre-E were patient-matched. | ||||||||||
| Sample scope | Multiisolate | ||||||||||
| Release date | 2024-02-28 | ||||||||||
| Publication |
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| Grants |
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| Submitter | Yue He (william5218@126.com) | ||||||||||
| Organization | Shanghai Jiao Tong University School of Medicine | ||||||||||
| Submission date | 2023-02-13 |
| Resource name | Description |
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| BioSample (26) show | - |