| Accession |
PRJCA015251 |
| Title |
Molecular mechanism of highly pathogenic virus infection and pathogenicity |
| Relevance |
Medical |
| Data types |
Assembly
|
| Organisms |
Virus NG10
|
| Description |
For highly pathogenic viruses such as small RNA virus, herpes virus, yellow virus, etc., we plan to develop the construction of technical system for high-resolution structural research of virus particles by using freeze electron microscopy technology. By studying the three-dimensional structure and inhibition mechanism of virus particles, virus particles and receptors, antibodies, and invasion inhibitor complexes, propose theoretical methods for optimizing and improving the recombinant vaccine to form a rapid response to severe infectious diseases. The situation of effective response is the main implementation content and ultimate goal of this project. |
| Sample scope |
recombinant protein |
| Release date |
2023-02-28 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 30333166
|
Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths
|
J Virol
|
10.1128/JVI.01655-18
|
2018
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2017YFC0840301
|
emerging infectious disease
|
| National Natural Science Foundation of China (NSFC)
|
Major Research Plan
|
37670752
|
|
| Chinese Academy of Sciences (CAS)
|
Strategic Priority Research Program of Chinese Academy of Sciences (CAS)
|
XDB08020203
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Basic Research Program of China (973 Program)
|
2016DDJ1ZZ17
|
|
|
|
| Accessions in other database |
| Accession |
Database name |
| 2017YFC0840300
|
NCBI
|
|
|
| Submitter |
Yutao
Chen (ccy@ibp.ac.cn)
|
| Organization |
Institute of Biophysics, Chinese Academy of Sciences |
| Submission date |
2023-02-28 |
