Accession |
PRJCA015451 |
Title |
Development of multiplex drop-off digital PCR assays for hotspot mutation detection of KRAS, NRAS, BRAF and PIK3CA in the plasma of colorectal cancer patients |
Relevance |
Medical |
Data types |
clinical data
|
Organisms |
Homo sapiens
|
Description |
We developed novel multiplex drop-off digital PCR (MDO-dPCR) assays, by combining amplitude-/ratio-based multiplexing with drop-off/double drop-off strategies, which allow for detection of at least 69 most frequent hotspot mutations in all four genes with only three reactions. |
Sample scope |
Monoisolate |
Release date |
2023-03-09 |
Grants |
Agency |
program |
Grant ID |
Grant title |
No funding support
|
|
|
|
|
Submitter |
Huiqin
Jiang (jiang.huiqin@zs-hospital.sh.cn)
|
Organization |
Zhongshan Hospital, Fudan University |
Submission date |
2023-03-09 |