Accession |
PRJCA015543 |
Title |
Calorie Restriction Remodels Hepatic Chromatin Landscape and Bile Acid Metabolism by Modulating the Gut Microbiota |
Relevance |
Medical |
Data types |
Epigenomics
|
Organisms |
Mus musculus
|
Description |
We investigate chromatin modifications, gene expression, as well as alterations in microbiota in a CR mouse model. Collectively, short-term CR led to changed gut microbial diversity and bile acid metabolism, improving energy expenditure. |
Sample scope |
Monoisolate |
Release date |
2023-03-16 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
37122023
|
Caloric restriction remodels the hepatic chromatin landscape and bile acid metabolism by modulating the gut microbiota
|
Genome Biology
|
10.1186/s13059-023-02938-5
|
2023
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
|
82173548
|
|
|
Submitter |
Bai
shengjun (sjbai@njfu.edu.cn)
|
Organization |
Nanjing Medical University |
Submission date |
2023-03-14 |