Accession PRJCA015643
Title Structural and functional studies of sperm-specific key membrane protein complexes
Relevance Medical
Data types PDB
Organisms Homo sapiens
Description By integrating various techniques such as single-particle cryo-electron microscopy, cryo-electron tomography, phage display antibody screening, as well as electrophysiology, substrate transport assays, and other biochemical experiments, a systematic elucidation of the working mechanisms of some key protein complexes is achieved, focusing on signal perception and response.
Sample scope PDB
Release date 2023-03-22
Publication
PubMed ID Article title Journal name DOI Year
34108458 Structure and mechanism of the human NHE1-CHP1 complex Nature Communications 10.1038/s41467-021-23496-z 2021
34552241 Nature 10.1038/s41586-021-03936-y 2021
34731621 Cell Reports 10.1016/j.celrep.2021.109931 2021
35277491 Nature Communications 10.1038/s41467-022-28808-5 2022
35165458 Nature Structural Molecular Biology 10.1038/s41594-022-00726-6 2022
35440630 Nature Communications 10.1038/s41467-022-29728-0 2022
35613257 Science Advances 10.1126/sciadv.abn3925 2022
35680945 Nature Communications 10.1038/s41467-022-31031-x 2022
Grants
Agency program Grant ID Grant title
Chinese Academy of Sciences (CAS) Strategic Priority Research Program of Chinese Academy of Sciences (CAS) XDB37000000 Structural and functional studies of sperm-specific key membrane protein complexes
Submitter Yanli Dong (dongyl@ibp.ac.cn)
Organization Institute of Biophysics, Chinese Academy of Sciences
Submission date 2023-03-18

Project Data

Resource name Description