| Accession |
PRJCA015994 |
| Title |
Identification and functional verification of CITED2 gene promoter region in patients with patent ductus arteriosus |
| Relevance |
Medical |
| Data types |
Genome sequencing and assembly
|
| Organisms |
Homo sapiens
|
| Description |
Patent ductus arteriosus (PDA) is a common congenital heart malformation. Genetic variants in the CITED2 coding region are known to be significantly associated with cardiac malformations, but the role of variants in the CITED2 promoter region in the development of PDA remains unclear. In this study, we investigated CITED2 promoter variants in the DNA of 646 subjects, including 353 PDA patients and 293 unrelated healthy controls, by Sanger sequencing. |
| Sample scope |
Monoisolate |
| Release date |
2023-04-01 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81870288/82170353
|
|
|
|
| Submitter |
Zhuo
Chen (czchloe@163.com)
|
| Organization |
TEDA International Cardiovascular Hospital |
| Submission date |
2023-04-01 |
