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项目编号 PRJCA016426
项目标题 Precise Microdissection of Gastric Mixed Adeno-neuroendocrine Carcinoma Reveals its Genomic Landscape and Evolutionary Clonal Origins
涉及领域 Medical
数据类型 Exome
Genome sequencing
物种名称 Homo sapiens
描述信息 Gastric mixed adenoneuroendocrine carcinoma (MANEC) is a clinically aggressive and heterogeneous tumor composed of adenocarcinoma (ACA) and neuroendocrine carcinoma (NEC). The genomic properties and evolutionary clonal origins of MANEC remain unclear. We conducted whole-exome and multiregion sequencing (MRS) on 101 samples from 33 patients, including ACA and NEC components separated using laser-capture microdissection technology, to elucidate their evolutionary paths.
样品范围 Multiisolate
发布日期 2023-06-01
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
37285266 Precise microdissection of gastric mixed adeno-neuroendocrine carcinoma dissects its genomic landscape and evolutionary clonal origins Cell Reports 10.1016/j.celrep.2023.112576 2023
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) General Program 82073377
National Natural Science Foundation of China (NSFC) General Program 81772587
National Natural Science Foundation of China (NSFC) General Program 82002470
National Natural Science Foundation of China (NSFC) General Program 82172861
Natural Science Foundation of Guangdong 2021A1515012439
Natural Science Foundation of Guangdong 2021A1515011743
Science and Technology Program of Guangdong 2019B020227002
CAMS Innovation Fund for Medical Sciences 2019-I2M-5-036
China Postdoctoral Science Foundation 2020M672998
Outstanding Young Talents Training Plan and Medical Scientist Program of Sun Yat-Sen University Cancer Center NA
提交者 Rui-hua Xu (xurh@sysucc.org.cn)
提交单位 Sun Yat-sen University
提交日期 2023-04-20

项目包含数据信息

资源名称 描述
BioSample (185)  show -