| Accession |
PRJCA016484 |
| Title |
Dual Identification and Analysis of Differentially Expressed Transcripts of breast cancer cells and Toxoplasma gondii during in vitro Infection |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Toxoplasma gondii
Homo sapiens
|
| Description |
To identify and analyze transcriptome changes of Toxoplasma gondii (T. gondii) and breast cancer cells after their interaction, RNA was extracted from the infected cell samples, and then was sequenced by Illumina NovaSeq 6000. In the present study, T. gondii RH strain tachyzoites were added to human breast cancer cells (MCF-7 cells and MDA-MB-231 cells) with MOI =4:1, while T. gondii ME49 strain tachyzoites were added to these cells with MOI=16:1. After 48 hours infection, RNA was extracted. |
| Sample scope |
Multispecies |
| Release date |
2023-09-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38654350
|
Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome
|
Cancer Cell International
|
10.1186/s12935-024-03333-1
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81973115
|
|
| Science and Technology Planning Project of Guangdong Province, China
|
|
2019B030316002
|
|
|
|
| Submitter |
Zefang
Ren (renzef@mail.sysu.edu.cn)
|
| Organization |
Sun Yat-sen University |
| Submission date |
2023-04-23 |
