| Accession |
PRJCA016564 |
| Title |
Structural basis for transcription and replication of SARS-CoV-2 |
| Relevance |
Medical |
| Data types |
protein 3D structure data
|
| Organisms |
Severe acute respiratory syndrome coronavirus 2
|
| Description |
This study focuses on the mechanisms of RNA transcription and replication of the SARS-CoV-2, and systematically investigates the three-dimensional complex of RNA polymerase nsp12 and primase nsp7/8. The structure of C-RTC and inhibitor complexes will be investigated to design new or improve existing antiviral drugs. |
| Sample scope |
Synthetic |
| Release date |
2023-04-25 |
| Publication |
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2020YFA0707501
|
Basic research on the molecular mechanism and prevention and control of SARS-CoV-2 infection replication
|
|
|
| Submitter |
Yucen
Huang (huangyc_14@163.com)
|
| Organization |
Tsinghua University |
| Submission date |
2023-04-25 |
